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Beyond antibiotic resistance: the <i>whiB7</i> transcription factor coordinates an adaptive response to alanine starvation in mycobacteria

2023-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Pathogenic mycobacteria are a significant cause of morbidity and mortality worldwide. These bacteria are highly intrinsically drug resistant, making infections challenging to treat. The conserved whiB7 stress response is a key contributor to mycobacterial intrinsic drug resistance. Although we have a comprehensive structural and biochemical understanding of WhiB7, the complex set of signals tha...

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Identifiers and source

Literature Corpus work
5f47eda7-b2de-5671-9a23-e3ce53b489b5
DOI
10.1101/2023.06.02.543512
Open publication

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Beyond antibiotic resistance: the <i>whiB7</i> transcription factor coordinates an adaptive response to alanine starvation in mycobacteriaDOI 10.1101/2023.06.02.543512
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