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Article

Mycobacterium abscessus WhiB7 Regulates a Species-Specific Repertoire of Genes To Confer Extreme Antibiotic Resistance.

Antimicrobial agents and chemotherapy - 1 Nov 2017

Hurst-Hess Kelley, Rudra Paulami, Ghosh Pallavi

Abstract excerpt

Mycobacterium abscessus causes acute and chronic bronchopulmonary infection in patients with chronic lung damage, of which cystic fibrosis (CF) patients are particularly vulnerable. The major threat posed by this organism is its high intrinsic antibiotic resistance. A typical treatment regimen involves a 6- to 12-month-long combination therapy of clarithromycin and amikacin, with cure rates below 50% and multiple...

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PMID: 28874378
DOI: 10.1128/AAC.01347-17
PMCID: PMC5655061

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Mycobacterium abscessus WhiB7 Regulates a Species-Specific Repertoire of Genes To Confer Extreme Antibiotic Resistance.PMID 28874378Read ↗

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