Article

Lsr2, a pleiotropic regulator at the core of the infectious strategy of <i>Mycobacterium abscessus</i>

2023-12-12

Abstract excerpt

<h4>ABSTRACT</h4> Mycobacterium abscessus is a non-tuberculous mycobacterium, causing lung infections in cystic fibrosis patients. During pulmonary infection, M. abscessus switches from smooth (Mabs-S) to rough (Mabs-R) morphotypes, the latter being hyper-virulent. Previously, we isolated the lsr2 gene as differentially expressed during S-to-R transition. lsr2 encodes a pleiotropic transcription factor that fa...

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Literature Corpus work: 448375bc-f194-5a8d-b073-3fb59f41c7ef
DOI: 10.1101/2023.12.12.571305

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