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Article

Ancestral antibiotic resistance in <i>Mycobacterium tuberculosis</i>

15 Aug 2005

Abstract excerpt

Chemotherapeutic options to treat tuberculosis are severely restricted by the intrinsic resistance of Mycobacterium tuberculosis to the majority of clinically applied antibiotics. Such resistance is partially provided by the low permeability of their unique cell envelope. Here we describe a complementary system that coordinates resistance to drugs that have penetrated the envelope, allowing mycobacteria to...

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Identifiers

PMID: 16103351
DOI: 10.1073/pnas.0505446102

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