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Article

Aminoglycoside cross-resistance in Mycobacterium tuberculosis due to mutations in the 5' untranslated region of whiB7.

Antimicrobial agents and chemotherapy - 1 Apr 2013

Reeves Analise Z, Campbell Patricia J, Sultana Razvan, Malik Seidu, Murray Megan, Plikaytis Bonnie B, Shinnick Thomas M, Posey James E

Abstract excerpt

Since the discovery of streptomycin's bactericidal activity against Mycobacterium tuberculosis, aminoglycosides have been utilized to treat tuberculosis (TB). Today, the aminoglycosides kanamycin and amikacin are used to treat multidrug-resistant (MDR) TB, and resistance to any of the second-line...

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Identifiers

PMID: 23380727
DOI: 10.1128/AAC.02191-12
PMCID: PMC3623337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23380727-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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