Article

The stress response factor SigH mediates intrinsic resistance to multiple antibiotics in <i>Mycobacterium abscessus</i>

2025-03-10

Abstract excerpt

Mycobacterium abscessus (Mab) causes pulmonary diseases with limited treatment options due to its high level of intrinsic resistance to available drugs. Mab possesses complex and poorly understood drug resistance mechanisms. Identifying new drug targets and gaining a deeper understanding of drug resistance mechanisms are essential for discovering novel therapeutic alternatives. Here, we investigated the role of a...

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Literature Corpus work: a254370a-43c2-52d5-a75b-7adce9f3d677
DOI: 10.1101/2025.03.04.641476

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