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Article

The Eyes Absent proteins in development and in developmental disorders.

Biochemical Society transactions - 30 Jun 2021

Soni Upendra Kumar, Roychoudhury Kaushik, Hegde Rashmi S

Abstract excerpt

The Eyes Absent (EYA) transactivator-phosphatase proteins are important contributors to cell-fate determination processes and to the development of multiple organs. The transcriptional regulatory activity as well as the protein tyrosine phosphatase activities of the EYA proteins can independently contribute to proliferation, differentiation, morphogenesis and tissue homeostasis in different contexts. Aberrant EYA...

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Identifiers

PMID: 34196366
DOI: 10.1042/BST20201302
PMCID: PMC8286820

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The Eyes Absent proteins in development and in developmental disorders.PMID 34196366Read ↗

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WDR1 is a novel EYA3 substrate and its dephosphorylation induces modifications of the cellular actin cytoskeleton.Semantic proximity Read ↗

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