Article

Metacell-based differential expression analysis identifies cell type specific temporal gene response programs in COVID-19 patient PBMCs

2023-12-15

Abstract excerpt

<h4>Background</h4> By resolving cellular heterogeneity in a biological sample, single cell RNA sequencing (scRNA-seq) can detect gene expression and its dynamics in different cell types. Its application to time-series samples can thus identify temporal genetic programs active in different cell types, for example, immune cells’ responses to viral infection. However, current scRNA-seq analysis need improvement. Tw...

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Literature Corpus work: 53b36b9b-cdd4-5c31-8107-71f407e14690
DOI: 10.1101/2023.12.14.571774

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