Article

Identifying genetic variants that influence the abundance of cell states in single-cell data

2023-11-15

Abstract excerpt

<h4>Introductory Paragraph</h4> To understand genetic mechanisms driving disease, it is essential but difficult to map how risk alleles affect the composition of cells present in the body. Single-cell profiling quantifies granular information about tissues, but variant-associated cell states may reflect diverse combinations of the profiled cell features that are challenging to predefine. We introduce GeNA (Genoty...

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Literature Corpus work: 163887e5-607a-5e13-b5f9-0e6fe050ce48
DOI: 10.1101/2023.11.13.566919

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