Article

Expression QTLs in single-cell sequencing data

2022-08-15

Abstract excerpt

<h4> A bstract </h4> Single nucleotide polymorphisms (SNPs) are important drivers of gene expression variation and downstream phenotypes including disease risk. Single-cell RNA-sequencing (scRNA-seq) allows an unprecedented exploration of cell-type specific associations between gene expression levels and genotypes, but current methods rely on pseudobulk approaches that use composite expression values across cel...

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Literature Corpus work: 1f713710-41fb-5a2a-95f0-d3d5d1d3c935
DOI: 10.1101/2022.08.14.503915

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