Article

E46K α-Synuclein Mutation Inhibits Cdc42EP2 Expression to Differentially Attenuate Neurite Outgrowth in SK-N-SH Cells

2024-11-26

Abstract excerpt

<h4>Background: </h4> /Objectives: α-Synuclein (α-syn) protein is a major pathological agent of familial Parkinson's disease (PD), and its levels and aggregations determine neurotoxicity in PD pathogenesis. Although the pathophysiological functions of α-syn have been extensively studied, its biological functions remain elusive, and there are reports of wild-type (WT) α-syn and two missense...

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Literature Corpus work: 00c0458f-fdee-5e19-849e-a10352bc9b5a
DOI: 10.20944/preprints202411.1879.v1

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