Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LncRNA-T199678 Mitigates α-Synuclein-Induced Dopaminergic Neuron Injury via miR-101-3p

24 Nov 2020

Abstract excerpt

Parkinson's disease (PD) is the second most common neurodegenerative disorder characterized by dopaminergic neuron death and the abnormal accumulation and aggregation of α-synuclein (α-Syn) in the substantia nigra (SN). Although the abnormal accumulation of α-Syn can solely promote and accelerate the progress of PD, the underlying molecular mechanisms remain unknown. Mounting evidence confirms that the abnormal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Parkinson's Disease Mechanisms and Treatments
Share to RNA regulation and disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33328976
DOI: 10.3389/fnagi.2020.599246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LncRNA-T199678 Mitigates α-Synuclein-Induced Dopaminergic Neuron Injury via miR-101-3pPMID 33328976Read ↗

Inhibition of miR-937-3p by targeting SNCB ameliorates rotenone-induced toxicity in SH- SY5Y cells by reducing alpha-synuclein aggregation and apoptosisSemantic proximity Read ↗

ROLE OF MICRORNAS IN THE PATHOGENESIS OF PARKINSON'S DISEASESemantic proximity Read ↗

MicroRNAs: Game Changers in the Regulation ofα-Synuclein in Parkinson’s DiseaseSemantic proximity Read ↗

Post-transcriptional Regulation of α-Synuclein Expression by mir-7 and mir-153Semantic proximity Read ↗

α-Synuclein Induces Alterations in Adult Neurogenesis in Parkinson Disease Models via p53-mediated Repression of Notch1Semantic proximity Read ↗

α-Synuclein and Mechanisms of Epigenetic RegulationSemantic proximity Read ↗

Repression of α-synuclein expression and toxicity by microRNA-7Semantic proximity Read ↗

Mitochondrial ROS-mediated post-transcriptional regulation of α-synuclein through miR-7 and miR-153Semantic proximity Read ↗

miR-486-3p Influences the Neurotoxicity of a-Synuclein by Targeting the SIRT2 Gene and the Polymorphisms at Target Sites Contributing to Parkinson’s DiseaseSemantic proximity Read ↗

Autophagy‑regulating miRNAs: Novel therapeutic targets for Parkinson's disease (Review)Semantic proximity Read ↗

MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System AtrophySemantic proximity Read ↗

The yin and yang of α-synuclein-associated epigenetics in Parkinson’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.