Article
Homeostasis Back and Forth: An Eco-Evolutionary Perspective of Cancer
2016-12-06
Abstract excerpt
The role of genetic mutations in cancer is indisputable: they are a key source of tumor heterogeneity and drive its evolution to malignancy. But the success of these new mutant cells relies on their ability to disrupt the homeostasis that characterizes healthy tissues. Mutated clones unable to break free from intrinsic and extrinsic homeostatic controls will fail to establish a tumor. Here we will discuss, through...
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Identifiers and source
- Literature Corpus work
- 004e1ec3-aa62-51d5-865b-916de45db5ce
- DOI
- 10.1101/092023