Article
A new cancer progression model: from synthetic tumors to real data and back
2026-02-09
Abstract excerpt
Intratumor heterogeneity (ITH) arises from the combined effects of genetic alterations, clonal interactions, and environmental constraints, and plays a central role in therapeutic resistance and disease progression. While ITH has been extensively documented in empirical tumor data, the scientific debate regarding the biological mechanisms underlying this heterogeneity remains complex, highlighting the need for can...
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Identifiers and source
- Literature Corpus work
- a1e83dce-6132-5e3d-84ed-fb3ab191efb9
- DOI
- 10.64898/2026.02.06.704299