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Article

Changing mutational and adaptive landscapes and the genesis of cancer.

Biochimica et biophysica acta. Reviews on cancer - 1 Apr 2017

Liggett L Alexander, DeGregori James

Abstract excerpt

By the time the process of oncogenesis has produced an advanced cancer, tumor cells have undergone extensive evolution. The cellular phenotypes resulting from this evolution have been well studied, and include accelerated growth rates, apoptosis resistance, immortality, invasiveness, and immune evasion. Yet with all of our current knowledge of tumor biology, the details of early oncogenesis have been difficult to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28167050
DOI: 10.1016/j.bbcan.2017.01.005
PMCID: PMC5557501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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