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Article

Cancer as an evolutionary and ecological process.

Nature reviews. Cancer - 1 Dec 2006

Merlo Lauren M F, Pepper John W, Reid Brian J, Maley Carlo C

Abstract excerpt

Neoplasms are microcosms of evolution. Within a neoplasm, a mosaic of mutant cells compete for space and resources, evade predation by the immune system and can even cooperate to disperse and colonize new organs. The evolution of neoplastic cells explains both why we get cancer and why it has been so difficult to cure. The tools of evolutionary biology and ecology are providing new insights into neoplastic...

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Identifiers

PMID: 17109012
DOI: 10.1038/nrc2013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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