Article
Genetic markers in clinically well defined patients with ulcerative colitis (UC).
Clinical and experimental immunology - 1 Feb 1999
Bouma G, Crusius J B, García-González M A, Meijer B U, Hellemans H P, Hakvoort R J, Schreuder G M, Kostense P J, Meuwissen S G, Peña A S
Abstract excerpt
Results of genetic association studies in UC are conflicting. We propose that the power of candidate gene studies will increase when disease heterogeneity is taken into account. Phenotype frequencies of molecularly defined HLA-DR alleles, polymorphisms in the tumour necrosis factor-alpha (TNF-alp...
Topics
- Adolescent
- Adult
- Aged
- Child
- Colitis, Ulcerative
- Cytokines
- Female
- Gene Frequency
- Genetic Markers
- HLA-DR Antigens
- Haplotypes
- Humans
- Interleukin 1 Receptor Antagonist Protein
- Interleukin-1
- Lymphotoxin-alpha