Article
Clinical and genetic heterogeneity in Mexican patients with ulcerative colitis.
Human immunology - 1 Jan 2003
Yamamoto-Furusho Jesús K, Uscanga Luis F, Vargas-Alarcón Gilberto, Ruiz-Morales Jorge A, Higuera Lorena, Cutiño Teresa, Rodríguez-Pérez José Manuel, Villarreal-Garza Cynthia, Granados Julio
Abstract excerpt
Ulcerative colitis (UC) is an inflammatory bowel disease of unknown etiology. Genetic factors implied on its onset and severity may include genes located within the class II major histocompatibility complex (MHC) region. The aim of this study was to determine the relationship between human leukocyte antigen (HLA)-DRB1 alleles with the clinical disease patterns of UC in Mexican Mestizo patients. High-resolution...
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