Article
Positive and negative associations of distinct HLA-DR2 subtypes with ulcerative colitis (UC).
Clinical and experimental immunology - 1 Jun 1997
De La Concha E G, Fernandez-Arquero M, Santa-Cruz S, Lopez-Nava G, Figueredo M A, Diaz-Rubio M, Garcia-Paredes J
Abstract excerpt
In UC, as in many other diseases with a suspected autoimmune etiology or pathogenesis, an association with certain HLA class II specificities has been investigated. In the Japanese, several studies have shown a positive association with DR2, but in Caucasian populations the results are conflicting. Therefore we undertook a study of HLA class II gene association with UC in a large group of white Madrid patients...
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