Article
HLA class II gene frequencies in Crohn's disease: a population based analysis in Germany.
Gut - 1 Apr 1996
Reinshagen M, Loeliger C, Kuehnl P, Weiss U, Manfras B J, Adler G, Boehm B O
Abstract excerpt
BACKGROUND: Ulcerative colitis is the only known inflammatory bowel disease associated with particular HLA alleles. Whereas the association with the HLA-DRB1*15 allele has been described in several independent studies for ulcerative colitis, no contribution of HLA alleles to susceptibility in Crohn's disease has yet been shown. AIM: This study was designed to study the strength of association of HLA class II...
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