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Article

Tumor necrosis factor receptor gene polymorphisms in Crohn's disease: association with clinical phenotypes.

The American journal of gastroenterology - 1 May 2005

Waschke Kevin A, Villani Alexandra-Chloe, Vermeire Severine, Dufresne Line, Chen Tsao-Chun, Bitton Alain, Cohen Albert, Thomson Alan B R, Wild Gary E

Abstract excerpt

OBJECTIVES: Crohn's disease (CD) is a chronic multifactorial disorder with diverse clinical features that are influenced by a heterogeneous set of genetic factors. TNF-alpha/TNF receptor interactions play a pivotal role in the pathogenesis of the inflammatory response. Our purpose was to determine whether single nucleotide polymorphisms (SNPs) in the TNF receptors confer susceptibility to Crohn's disease and...

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Source

Identifiers

PMID: 15842589
DOI: 10.1111/j.1572-0241.2005.40534.x

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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