Article
Role of chromosome X in the Sabra rat model of salt-sensitive hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 1999
Yagil C, Sapojnikov M, Kreutz R, Zürcher H, Ganten D, Yagil Y
Abstract excerpt
We carried out a total genome screen in the Sabra rat model of hypertension to detect salt-susceptibility genes. We previously reported in male animals the presence of 2 major quantitative trait loci (QTLs) on chromosome 1 that together accounted for most of the difference in the blood pressure (...
Topics
- Animals
- Chromosome Mapping
- Crosses, Genetic
- Female
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Genotype
- Hypertension
- Israel
- Male
- Microsatellite Repeats
- Phenotype
- Polymorphism, Genetic
- Quantitative Trait, Heritable
- Rats
- Rats, Inbred Strains
- Sex Characteristics
