Article
Role of chromosome X in the Sabra rat model of salt-sensitive hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 1999
Yagil C, Sapojnikov M, Kreutz R, Zürcher H, Ganten D, Yagil Y
Abstract excerpt
We carried out a total genome screen in the Sabra rat model of hypertension to detect salt-susceptibility genes. We previously reported in male animals the presence of 2 major quantitative trait loci (QTLs) on chromosome 1 that together accounted for most of the difference in the blood pressure (BP) response to salt loading between Sabra hypertension-prone rats (SBH/y) and Sabra hypertension-resistant rats...
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