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Article

Identification of hypertension susceptibility loci on rat chromosome 12.

Hypertension (Dallas, Tex. : 1979) - 1 Oct 2012

Flister Michael J, Prisco Sasha Z, Sarkis Allison B, O'Meara Caitlin C, Hoffman Matthew, Wendt-Andrae Jaime, Moreno Carol, Lazar Jozef, Jacob Howard J

Abstract excerpt

Previous studies have identified multiple blood pressure and renal disease quantitative trait loci located on rat chromosome 12. In the present study, we narrowed blood pressure loci using a series of overlapping Dahl salt-sensitive/Mcwi (SS)-12 Brown Norway (BN) congenic lines. We found that transferring 6.1 Mb of SS chromosome 12 (13.4-19.5 Mb) onto the consomic SS-12BN background significantly elevated blood...

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Identifiers

PMID: 22868394
DOI: 10.1161/HYPERTENSIONAHA.112.198200
PMCID: PMC3873777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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