Article
Sex-specific QTLs and interacting loci underlie salt-sensitive hypertension and target organ complications in Dahl S/jrHS hypertensive rats.
Physiological genomics - 16 Aug 2006
Herrera Victoria L M, Tsikoudakis Aristides, Ponce Lorenz R B, Matsubara Yuichi, Ruiz-Opazo Nelson
Abstract excerpt
Sex-specific differences in polygenic (essential) hypertension are commonly attributed to the role of sex steroid hormone-receptor systems attenuating sex-common disease mechanisms in premenopausal women. However, emerging observations indicate sex-specific genetic susceptibility in various traits, thus requiring systematic study. Here we report a comparative analysis of independent total genome scans for...
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