Article
Salt susceptibility maps to chromosomes 1 and 17 with sex specificity in the Sabra rat model of hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 1998
Yagil C, Sapojnikov M, Kreutz R, Katni G, Lindpaintner K, Ganten D, Yagil Y
Abstract excerpt
Random genome screening was initiated in the Sabra rat model of hypertension in search of genes that account for salt sensitivity or salt resistance in terms of the development of hypertension. Female salt-sensitive Sabra hypertension-prone (SBH/y) rats were crossed with male salt-resistant Sabra hypertension-resistant (SBN/y) rats, resulting in an F2 cohort consisting of 100 males and 132 females. Systolic blood...
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