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Genetic dissection of proteinuria in the Sabra rat.

Physiological genomics - 13 Mar 2006

Yagil Chana, Sapojnikov Marina, Wechsler Alexander, Korol Abraham, Yagil Yoram

Abstract excerpt

The pathophysiology underlying proteinuria remains incompletely understood and warrants further research. We currently initiated the investigation of the genetic basis of proteinuria in the Sabra rat, a model of salt susceptibility that we showed previously to be also a model of spontaneous proteinuria that is unrelated to salt loading or development of hypertension. We applied the total genome scan strategy in...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Genetic Linkage
Genotype
Lod Score
Male
Models, Animal
Proteins
Proteinuria
Quantitative Trait Loci
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats, Inbred Strains

Time Factors

Source

Identifiers

PMID: 16390874
DOI: 10.1152/physiolgenomics.00235.2005

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