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Article

A biometrical genome search in rats reveals the multigenic basis of blood pressure variation.

Genome research - 1 Sept 1995

Schork N J, Krieger J E, Trolliet M R, Franchini K G, Koike G, Krieger E M, Lander E S, Dzau V J, Jacob H J

Abstract excerpt

A genome-wide search for multiple loci influencing salt-loaded systolic blood pressure (NaSBP) variation among 188 F2 progeny from a cross between the Brown-Norway and spontaneously hypertensive rat strains was pursued in an effort to gain insight into the polygenic basis of blood pressure regulation. The results suggest that loci within five to six genomic regions collectively explain approximately 43% of the...

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PMID: 9132270
DOI: 10.1101/gr.5.2.164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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