A biometrical genome search in rats reveals the multigenic basis of blood pressure variation.

doi:10.1101/gr.5.2.164

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Article

A biometrical genome search in rats reveals the multigenic basis of blood pressure variation.

Genome research - 1 Sept 1995

Schork N J, Krieger J E, Trolliet M R, Franchini K G, Koike G, Krieger E M, Lander E S, Dzau V J, Jacob H J

Abstract excerpt

A genome-wide search for multiple loci influencing salt-loaded systolic blood pressure (NaSBP) variation among 188 F2 progeny from a cross between the Brown-Norway and spontaneously hypertensive rat strains was pursued in an effort to gain insight into the polygenic basis of blood pressure regula...

Topics

Animals
Biometry
Blood Pressure
Crosses, Genetic
Female
Genetic Variation
Male
Rats
Rats, Inbred BN
Rats, Inbred SHR

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