Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Defining a rat blood pressure quantitative trait locus to a <81.8 kb congenic segment: comprehensive sequencing and renal transcriptome analysis.

Physiological genomics - 1 Oct 2010

Gopalakrishnan K, Saikumar J, Peters C G, Kumarasamy S, Farms P, Yerga-Woolwine S, Toland E J, Schnackel W, Giovannucci D R, Joe B

Abstract excerpt

Evidence from multiple linkage and genome-wide association studies suggest that human chromosome 2 (HSA2) contains alleles that influence blood pressure (BP). Homologous to a large segment of HSA2 is rat chromosome 9 (RNO9), to which a BP quantitative trait locus (QTL) was previously mapped. The objective of the current study was to further resolve this BP QTL. Eleven congenic strains with introgressed segments...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Congenic
Share to Base Pairing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Blood Pressure

Share to Chromosomes, Mammalian

Share to Down-Regulation

Share to Kaplan-Meier Estimate

Share to Kidney

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 20716646
DOI: 10.1152/physiolgenomics.00122.2010
PMCID: PMC2957796

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Defining a rat blood pressure quantitative trait locus to a <81.8 kb congenic segment: comprehensive sequencing and renal transcriptome analysis.PMID 20716646Read ↗

Locating a blood pressure quantitative trait locus within 117 kb on the rat genome: substitution mapping and renal expression analysis.Semantic proximity Read ↗

Identification of hypertension susceptibility loci on rat chromosome 12.Semantic proximity Read ↗

Fine-mapping and comprehensive transcript analysis reveals nonsynonymous variants within a novel 1.17 Mb blood pressure QTL region on rat chromosome 10.Semantic proximity Read ↗

Congenic mapping of a blood pressure QTL region on rat chromosome 10 using the Dahl salt-sensitive rat with introgressed alleles from the Milan normotensive strain.Semantic proximity Read ↗

Dissection of chromosome 18 blood pressure and salt-sensitivity quantitative trait loci in the spontaneously hypertensive rat.Semantic proximity Read ↗

High-resolution mapping of a novel rat blood pressure locus on chromosome 9 to a region containing the Spp2 gene and colocalization of a QTL for bone mass.Semantic proximity Read ↗

Fine mapping of epistatic genetic determinants of blood pressure on rat chromosome 5.Semantic proximity Read ↗

Linkage analysis and construction of a congenic strain for a blood pressure QTL on rat chromosome 9.Semantic proximity Read ↗

Narrowing a region on rat chromosome 13 that protects against hypertension in Dahl SS-13BN congenic strains.Semantic proximity Read ↗

Congenic mapping and sequence analysis of the Renin locus.Semantic proximity Read ↗

Refined mapping of a hypertension susceptibility locus on rat chromosome 12.Semantic proximity Read ↗

The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.