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Article

Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population.

Biochemical and biophysical research communications - 27 Jan 1999

Yasar U, Eliasson E, Dahl M L, Johansson I, Ingelman-Sundberg M, Sjöqvist F

Abstract excerpt

Cytochrome P450 2C9 (CYP2C9) catalysis the metabolism of important drugs such as phenytoin, S-warfarin, tolbutamide, losartan, torasemide, and nonsteroidal anti-inflammatory drugs. A functional polymorphism of the CYP2C9 gene has been described. The variant alleles include CYP2C9*2 having a point mutation in exon 3 causing an Arg144Cys exchange, and CYP2C9*3 with a point mutation in exon 7 resulting in an...

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Identifiers

PMID: 9920790
DOI: 10.1006/bbrc.1998.9992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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