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Article

Rapid detection of CYP2C9*3 alleles by real-time fluorescence PCR based on SYBR Green.

Molecular genetics and metabolism - 1 Nov 1999

Hiratsuka M, Agatsuma Y, Mizugaki M

Abstract excerpt

CYP2C9 catalyzes the metabolism of important drugs such as phenytoin, S-warfarin, tolbutamide, losartan, and nonsteroidal anti-inflammatory drugs. A functional polymorphism of the CYP2C9 gene has been described. The single-base mutation of A1061C (Ile359Leu) in the CYP2C9 gene termed CYP2C9*3 was found at a frequency of about 2.1% in Japanese. We developed a rapid mutation analysis method for detecting the...

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Identifiers

PMID: 10562462
DOI: 10.1006/mgme.1999.2919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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