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Article

Genetic analysis of the human cytochrome P450 CYP2C9 locus.

Pharmacogenetics - 1 Oct 1996

Stubbins M J, Harries L W, Smith G, Tarbit M H, Wolf C R

Abstract excerpt

Cytochrome P450 CYP2C9 metabolizes a wide variety of clinically important drugs, including phenytoin, tolbutamide, warfarin and a large number of non-steroidal anti-inflammatory drugs. Previous studies have shown that even relatively conservative changes in the amino acid composition of this enzyme can affect both its activity and substrate specificity. To date six different human CYP2C9 cDNA sequences, as well...

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PMID: 8946475
DOI: 10.1097/00008571-199610000-00007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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