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Article

The impact of CYP2C9 genetics and oral contraceptives on cytochrome P450 2C9 phenotype.

Drug metabolism and disposition: the biological fate of chemicals - 1 May 2004

Sandberg Mia, Johansson Inger, Christensen Magnus, Rane Anders, Eliasson Erik

Abstract excerpt

CYP2C9-dependent drug metabolism is subject to large interindividual variation. To some extent, this is explained by genetic polymorphism with expression of enzyme variants that differ in catalytic activity. The aim of this study was to characterize the variation in CYP2C9 phenotype in relation to genotype, with further analysis of the CYP2C9 gene in metabolic outliers. A study population of 126 healthy white...

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Identifiers

PMID: 15100169
DOI: 10.1124/dmd.32.5.484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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