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Article

High frequency of mutations related to impaired CYP2C9 metabolism in a Caucasian population.

European journal of clinical pharmacology - 1 Apr 2001

García-Martín E, Martínez C, Ladero J M, Gamito F J, Agúndez J A

Abstract excerpt

OBJECTIVE: To search for ethnic variability in the impact of cytochrome P450 2C9 (CYP2C9) polymorphism. METHODS: CYP2C9 allelic variants related to impaired CYP2C9 metabolism were analysed in genomic DNA from 157 Spanish healthy subjects using amplification-restriction and sequencing procedures. RESULTS: The frequency for CYP2C9 mutated alleles is higher among the Spanish subjects analysed than that reported for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11372590
DOI: 10.1007/s002280100264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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