Article
Protein kinase C modulation of recombinant NMDA receptor currents: roles for the C-terminal C1 exon and calcium ions.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Feb 1999
Logan S M, Rivera F E, Leonard J P
Abstract excerpt
Protein kinase C (PKC) positively modulates NMDA receptor (NMDAR) currents. In contrast to previous reports, this study determines the importance of individual exons in the mechanism underlying the potentiation process by examining the complete set of eight naturally occurring splice variants exp...
Topics
- Animals
- Barium
- Calcium
- Chloride Channels
- DNA, Recombinant
- Electric Conductivity
- Exons
- Female
- Genetic Variation
- Ions
- Oocytes
- Phorbol 12,13-Dibutyrate
- Protein Kinase C
- Rats
- Receptors, N-Methyl-D-Aspartate
- Recombinant Proteins
- Xenopus laevis