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Article

Subunit interactions and AMPA receptor desensitization.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Aug 2001

Robert A, Irizarry S N, Hughes T E, Howe J R

Abstract excerpt

Most AMPA-type glutamate receptors (GluRs) exhibit rapid and virtually complete desensitization when activated by glutamate, and at some central synapses it is largely desensitization that determines the decay of EPSCs. However, the mechanisms underlying the conformation change that results in desensitization are not fully understood. AMPA receptor subunits that contain a single amino acid substitution have been...

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Identifiers

PMID: 11466429
PMCID: PMC6762644

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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