Article
Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor.
Neuron - 1 May 1993
Hollmann M, Boulter J, Maron C, Beasley L, Sullivan J, Pecht G, Heinemann S
Abstract excerpt
We have determined the gene structure for the NMDA receptor subunit gene NMDAR1. We found eight splice variants that arise from different combinations of a single 5' terminal exon insertion and three different 3' terminal exon deletions, relative to NMDAR1. We analyzed the modulation by Zn2+ of currents through homomeric receptors assembled from these splice variants and found that, in addition to its well-known...
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