Article
Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America - 15 Jul 1993
Durand G M, Bennett M V, Zukin R S
Abstract excerpt
The N-methyl-D-aspartate (NMDA) receptor NR1 gene encodes RNA that is alternatively spliced to generate at least seven variants. The variants arise from splicing in or out of three exons; one encodes a 21-amino acid insert in the N-terminal domain, and two encode adjacent sequences of 37 and 38 amino acids in the C-terminal domain. Splicing out of the second C-terminal exon deletes a stop codon and results in an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.