Article
Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C.
Proceedings of the National Academy of Sciences of the United States of America - 15 Jul 1993
Durand G M, Bennett M V, Zukin R S
Abstract excerpt
The N-methyl-D-aspartate (NMDA) receptor NR1 gene encodes RNA that is alternatively spliced to generate at least seven variants. The variants arise from splicing in or out of three exons; one encodes a 21-amino acid insert in the N-terminal domain, and two encode adjacent sequences of 37 and 38 a...
Topics
- Alternative Splicing
- Animals
- Binding Sites
- Gene Expression
- Genetic Variation
- Membrane Potentials
- Mesencephalon
- Oocytes
- Polyamines
- Protein Kinase C
- Receptors, N-Methyl-D-Aspartate
- Structure-Activity Relationship
- Tetradecanoylphorbol Acetate
- Xenopus laevis