Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation and modulation of concatemeric GABA-A receptors expressed in human embryonic kidney cells.

Molecular pharmacology - 1 Jun 2009

Akk Gustav, Li Ping, Bracamontes John, Steinbach Joe Henry

Abstract excerpt

We have employed whole-cell and single-channel electrophysiology to examine the kinetic and pharmacological properties of GABA-A receptors consisting of gamma2L-beta2-alpha1 and beta2-alpha1 subunit concatemeric constructs expressed in human embryonic kidney cells. Concatemeric receptors activate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Diazepam
Share to gamma-Aminobutyric Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ion Channel Gating

Share to Patch-Clamp Techniques

Share to Protein Multimerization

Share to Protein Subunits

Share to Receptors, GABA-A

Source

Open in PubMed Open full text

Identifiers

PMID: 19289569
DOI: 10.1124/mol.108.054510
PMCID: PMC2684887

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19289569-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation and modulation of concatemeric GABA-A receptors expressed in human embryonic kidney cells.PMID 19289569Read ↗

Steroid interaction with a single potentiating site is sufficient to modulate GABA-A receptor function.Semantic proximity Read ↗

Dual potentiating and inhibitory actions of a benz[e]indene neurosteroid analog on recombinant alpha1beta2gamma2 GABAA receptors.Semantic proximity Read ↗

Pregnenolone sulphate and Zn2+ inhibit recombinant rat GABA(A) receptor through different channel property.Semantic proximity Read ↗

Mechanism of potentiation of a dysfunctional epilepsy-linked mutated GABA(A) receptor by a neurosteroid (3alpha, 21-dihydroxy-5alpha-pregnan-20-one): transient kinetic investigations.Semantic proximity Read ↗

Contributions of different kainate receptor subunits to the properties of recombinant homomeric and heteromeric receptors.Semantic proximity Read ↗

Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate.Semantic proximity Read ↗

Two different mechanisms of disinhibition produced by GABAA receptor mutations linked to epilepsy in humans.Semantic proximity Read ↗

On the mechanism of alleviation by phenobarbital of the malfunction of an epilepsy-linked GABA(A) receptor.Semantic proximity Read ↗

Protein kinase C modulation of recombinant NMDA receptor currents: roles for the C-terminal C1 exon and calcium ions.Semantic proximity Read ↗

The desensitization pathway of GABAA receptors, one subunit at a time.Semantic proximity Read ↗

Potentiation of a neuronal nicotinic receptor via pseudo-agonist site.Semantic proximity Read ↗

Development of a Robust Mammalian Cell-based Assay for Studying Recombinant α4 β1/3 δ GABAA Receptor Subtypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.