Article
Synaptic targeting of N-methyl-D-aspartate receptor splice variants is regulated differentially by receptor activity.
Neuroscience - 1 Jan 2005
Pauly T, Schlicksupp A, Neugebauer R, Kuhse J
Abstract excerpt
The formation of postsynaptic clusters of various ligand-gated ion channels is regulated by receptor activity. Here we describe the developmental- and activity-dependent modification of N-methyl-D-aspartate (NMDA) receptor clustering in spinal cord neurons in vitro detected by immunofluorescence analysis using subunit and splice variant specific antibodies. NMDA receptors form synaptic and extrasynaptic clusters...
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