Article
Parental alleles of an imprinted mouse transgene replicate synchronously.
Developmental genetics - 1 Jan 1998
Shuster M, Dhar M S, Olins A L, Olins D E, Howell C Y, Gollin S M, Chaillet J R
Abstract excerpt
Molecular features of imprinted genes include differences in expression, methylation, and the timing of DNA replication between parental alleles. Whereas methylation differences always seem to be associated with differences in expression, differences in the timing of replication between parental homologs are not always seen at imprinted loci. These observations raise the possibility that differences in...
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