Article
Phenotypic variation in a genetically identical population of mice.
Molecular and cellular biology - 1 Sept 1997
Weichman K, Chaillet J R
Abstract excerpt
The parental alleles of an imprinted gene acquire their distinctive methylation patterns at different times in development. For the imprinted RSVIgmyc transgene, methylation of the maternal allele is established in the oocyte and invariably transmitted to the embryo. In contrast, the methylation of the paternal allele originates during embryogenesis. Here, we show that the paternal methylation pattern among mice...
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