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Article

Paternal imprints can be established on the maternal Igf2-H19 locus without altering replication timing of DNA.

Human molecular genetics - 1 Dec 2003

Cerrato Flavia, Dean Wendy, Davies Karen, Kagotani Kazuhiro, Mitsuya Kohzoh, Okumura Katsuzumi, Riccio Andrea, Reik Wolf

Abstract excerpt

Genomic imprinting in mammals marks the parental alleles in gametes, resulting in differential gene expression in offspring. A number of epigenetic features are associated with imprinted genes. These include differential DNA methylation, histone acetylation and methylation, subnuclear localization and DNA replication timing. While DNA methylation has been shown to be necessary both for establishment and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 14532328
DOI: 10.1093/hmg/ddg338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Paternal imprints can be established on the maternal Igf2-H19 locus without altering replication timing of DNA.PMID 14532328Read ↗

Allele-specific replication timing of imprinted gene regions.Semantic proximity Read ↗

Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactionsSemantic proximity Read ↗

CTCF regulates asynchronous replication of the imprinted H19/Igf2 domain.Semantic proximity Read ↗

Timing of establishment of paternal methylation imprints in the mouse.Semantic proximity Read ↗

Establishment and maintenance of H19 imprinting in the germline and preimplantation embryo.Semantic proximity Read ↗

Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization.Semantic proximity Read ↗

Acquisition of the H19 methylation imprint occurs differentially on the parental alleles during spermatogenesis.Semantic proximity Read ↗

Nonallelic transvection of multiple imprinted loci is organized by the H19 imprinting control region during germline development.Semantic proximity Read ↗

Role for DNA methylation in genomic imprinting.Semantic proximity Read ↗

Disruption of mesodermal enhancers for Igf2 in the minute mutant.Semantic proximity Read ↗

Imprinting mutations in the Beckwith—Wiedemann syndrome suggested by an altered imprinting pattern in the <i>IGF2–H19</i> domainSemantic proximity Read ↗

The H19 Imprinting Control Region Mediates Preimplantation Imprinted Methylation of Nearby Sequences in Yeast Artificial Chromosome Transgenic MiceSemantic proximity Read ↗

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