Article
An epigenetic state associated with areas of gene duplication.
Genome research - 1 Jun 2006
Gimelbrant Alexander A, Chess Andrew
Abstract excerpt
Asynchronous DNA replication is an epigenetically determined feature found in all cases of monoallelic expression, including genomic imprinting, X-inactivation, and random monoallelic expression of autosomal genes such as immunoglobulins and olfactory receptor genes. Most genes of the latter class were identified in experiments focused on genes functioning in the chemosensory and immune systems. We performed an...
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