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Article

Allele-specific replication timing of imprinted gene regions.

Nature - 29 Jul 1993

Kitsberg D, Selig S, Brandeis M, Simon I, Keshet I, Driscoll D J, Nicholls R D, Cedar H

Abstract excerpt

Several lines of evidence suggest that the paternal and maternal genomes may have different expression patterns in the developing organism and this has been confirmed by the identification of endogenous genes that are parentally imprinted in the mouse. Little is known about the precise mechanisms...

Topics

Alleles
Animals
Base Sequence
Cell Cycle
Cell Line
Crosses, Genetic
DNA Replication
Female
Genome
Humans
In Situ Hybridization, Fluorescence
Male
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Muridae

Time Factors

Transcription, Genetic

Source

Identifiers

PMID: 8332218
DOI: 10.1038/364459a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8332218-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Click a neighbor to travelStep 1 · 12 closest

Allele-specific replication timing of imprinted gene regions.PMID 8332218Read ↗

Asynchronous replication of imprinted genes is established in the gametes and maintained during development.Semantic proximity Read ↗

CTCF regulates asynchronous replication of the imprinted H19/Igf2 domain.Semantic proximity Read ↗

Parent-of-origin-specific DNA replication timing is confined to large imprinted regions.Semantic proximity Read ↗

Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization.Semantic proximity Read ↗

Reprogramming of DNA replication timing.Semantic proximity Read ↗

Paternal imprints can be established on the maternal Igf2-H19 locus without altering replication timing of DNA.Semantic proximity Read ↗

Replication timing properties within the mouse distal chromosome 7 imprinting cluster.Semantic proximity Read ↗

Factors affecting the timing and imprinting of replication on a mammalian chromosomeSemantic proximity Read ↗

Allele-specific replication timing in imprinted domains: absence of asynchrony at several loci.Semantic proximity Read ↗

Chromosomal coordination and differential structure of asynchronous replicating regions.Semantic proximity Read ↗

Sex-specific DNA-replication in the early mammalian embryoSemantic proximity Read ↗

Expression of H19 does not influence the timing of replication of the Igf2/H19 imprinted region.Semantic proximity Read ↗

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