Article
Evidence for a functional interaction between integrins and G protein-activated inward rectifier K+ channels.
The Journal of biological chemistry - 25 Dec 1998
McPhee J C, Dang Y L, Davidson N, Lester H A
Abstract excerpt
Heteromultimeric G protein-activated inward rectifier K+ (GIRK) channels, abundant in heart and brain, help to determine the cellular membrane potential as well as the frequency and duration of electrical impulses. The sequence arginine-glycine-aspartate (RGD), located extracellularly between the first membrane-spanning region and the pore, is conserved among all identified GIRK subunits but is not found in the...
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