Article
Evidence for a functional interaction between integrins and G protein-activated inward rectifier K+ channels.
The Journal of biological chemistry - 25 Dec 1998
McPhee J C, Dang Y L, Davidson N, Lester H A
Abstract excerpt
Heteromultimeric G protein-activated inward rectifier K+ (GIRK) channels, abundant in heart and brain, help to determine the cellular membrane potential as well as the frequency and duration of electrical impulses. The sequence arginine-glycine-aspartate (RGD), located extracellularly between the...
Topics
- Cell Compartmentation
- Cell Membrane
- Electric Conductivity
- G Protein-Coupled Inwardly-Rectifying Potassium Channels
- Integrins
- Mutation
- Potassium Channels
- Potassium Channels, Inwardly Rectifying
- Protein Binding
- Receptors, Muscarinic
