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Article

Effects of mutations in pleckstrin homology domain on beta-adrenergic receptor kinase activity in intact cells.

Biochemical and biophysical research communications - 27 Nov 1998

Touhara K

Abstract excerpt

beta-Adrenergic receptor kinase (betaARK) plays a pivotal role in phosphorylating and desensitizing G protein coupled receptors by virtue of pleckstrin homology (PH) domain-mediated membrane translocation. betaARK is localized to the specific membrane compartment by betagamma subunits of G proteins (Gbetagamma) and phosphatidylinositol phosphates that specifically and coordinately bind to the carboxyl and amino...

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Identifiers

PMID: 9837764
DOI: 10.1006/bbrc.1998.9722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of mutations in pleckstrin homology domain on beta-adrenergic receptor kinase activity in intact cells.PMID 9837764Read ↗

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