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Article

Mutation of protein kinase C phosphorylation site S1076 on alpha-subunits affects BK(Ca) channel activity in HEK-293 cells.

American journal of physiology. Lung cellular and molecular physiology - 1 Oct 2009

Zhu Shu, Browning Darren D, White Richard E, Fulton David, Barman Scott A

Abstract excerpt

Large conductance, calcium- and voltage-activated potassium (BK(Ca)) channels are important modulators of pulmonary vascular smooth muscle membrane potential, and phosphorylation of BK(Ca) channels by protein kinases regulates pulmonary arterial smooth muscle function. However, little is known about the effect of phosphorylating specific channel subunits on BK(Ca) channel activity. The present study was done to...

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Source

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Identifiers

PMID: 19592459
DOI: 10.1152/ajplung.90518.2008
PMCID: PMC2770791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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