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Article

A novel adenylyl cyclase detected in rapidly developing mutants of Dictyostelium.

The Journal of biological chemistry - 20 Nov 1998

Kim H J, Chang W T, Meima M, Gross J D, Schaap P

Abstract excerpt

Disruption of either the RDEA or REGA genes leads to rapid development in Dictyostelium. The RDEA gene product displays homology to certain H2-type phosphotransferases, while REGA encodes a cAMP phosphodiesterase with an associated response regulator. It has been proposed that RDEA activates REGA in a multistep phosphorelay. To test this proposal, we examined cAMP accumulation in rdeA and regA null mutants and...

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Identifiers

PMID: 9812977
DOI: 10.1074/jbc.273.47.30859

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Source receipt: pubmed, retrieved 7 Sept 2026.

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