Article
A novel adenylyl cyclase detected in rapidly developing mutants of Dictyostelium.
The Journal of biological chemistry - 20 Nov 1998
Kim H J, Chang W T, Meima M, Gross J D, Schaap P
Abstract excerpt
Disruption of either the RDEA or REGA genes leads to rapid development in Dictyostelium. The RDEA gene product displays homology to certain H2-type phosphotransferases, while REGA encodes a cAMP phosphodiesterase with an associated response regulator. It has been proposed that RDEA activates REGA...
Topics
- 1-Methyl-3-isobutylxanthine
- 3',5'-Cyclic-AMP Phosphodiesterases
- Adenylyl Cyclase Inhibitors
- Adenylyl Cyclases
- Animals
- Cyclic AMP
- Cyclic AMP-Dependent Protein Kinases
- DNA-Binding Proteins
- Dictyostelium
- Isoenzymes
- Mutation
