Article
Genome-wide expression analyses of gene regulation during early development of Dictyostelium discoideum.
Eukaryotic cell - 1 Aug 2003
Iranfar Negin, Fuller Danny, Loomis William F
Abstract excerpt
Using genome-wide microarrays, we recognized 172 genes that are highly expressed at one stage or another during multicellular development of Dictyostelium discoideum. When developed in shaken suspension, 125 of these genes were expressed if the cells were treated with cyclic AMP (cAMP) pulses at 6-min intervals between 2 and 6 h of development followed by high levels of exogenous cAMP. In the absence of cAMP...
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