Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adenylate cyclase A acting on PKA mediates induction of stalk formation by cyclic diguanylate at the Dictyostelium organizer.

Proceedings of the National Academy of Sciences of the United States of America - 17 Jan 2017

Chen Zhi-Hui, Singh Reema, Cole Christian, Lawal Hajara Mohammed, Schilde Christina, Febrer Melanie, Barton Geoffrey J, Schaap Pauline

Abstract excerpt

Coordination of cell movement with cell differentiation is a major feat of embryonic development. The Dictyostelium stalk always forms at the organizing tip, by a mechanism that is not understood. We previously reported that cyclic diguanylate (c-di-GMP), synthesized by diguanylate cyclase A (DgcA), induces stalk formation. Here we used transcriptional profiling of dgca- structures to identify target genes for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Cyclic AMP

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cyclic AMP-Dependent Protein Kinases

Share to Cyclic GMP

Share to Dictyostelium

Share to Genes, Protozoan

Share to Phosphorus-Oxygen Lyases

Share to Protozoan Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28057864
DOI: 10.1073/pnas.1608393114
PMCID: PMC5255622

Genes

ACR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adenylate cyclase A acting on PKA mediates induction of stalk formation by cyclic diguanylate at the Dictyostelium organizer.PMID 28057864Read ↗

Genome-wide expression analyses of gene regulation during early development of Dictyostelium discoideum.Semantic proximity Read ↗

An intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium.Semantic proximity Read ↗

A cAMP-phosphodiesterase controls PKA-dependent differentiation.Semantic proximity Read ↗

cAMP production by adenylyl cyclase G induces prespore differentiation in Dictyostelium slugs.Semantic proximity Read ↗

cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development.Semantic proximity Read ↗

An adenylyl cyclase that functions during late development of Dictyostelium.Semantic proximity Read ↗

Loss of cAMP-specific phosphodiesterase rescues spore development in G protein mutant in dictyostelium.Semantic proximity Read ↗

The polyketide MPBD initiates the SDF-1 signaling cascade that coordinates terminal differentiation in Dictyostelium.Semantic proximity Read ↗

A conserved signalling pathway for amoebozoan encystation that was co-opted for multicellular development.Semantic proximity Read ↗

Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium.Semantic proximity Read ↗

Protein kinase A regulates the Ras, Rap1 and TORC2 pathways in response to the chemoattractant cAMP in Dictyostelium.Semantic proximity Read ↗

Glycogen synthase kinase 3 regulates cell fate in Dictyostelium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.